Postdoc Positions at Duke

Below are some of the postdoctoral positions available at Duke University. Please note that this list is NOT comprehensive. If you do not see a position in your area of interest, you should directly contact Duke faculty who are working in your research area(s) to inquire about possible positions.

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual’s age, color, disability, genetic information, gender, gender identity, national origin, race, religion, sexual orientation, or veteran status.

Position Title Department Job Description Deadline to apply
Postdoctoral Associate, Duke Human Vaccine Institute Duke Human Vaccine Institute

The Duke Human Vaccine Institute and the Center for HIV/AIDS Vaccine Immunology; Immunogen Design (CHAVI-ID), providing national and international leadership in the fight against major infectious diseases, is currently recruiting for a Postdoctoral Associate position. The Duke Human Vaccine Institute (DHVI) is an interdisciplinary, interdepartmental institute dedicated to the study of basic and translational science required to understand host-pathogen interactions that can be translated to vaccines against human diseases. DHVI comprises a team of highly interactive investigators that have expertise in mucosal and systemic virology, molecular biology, microbiology and animal models. We are seeking a motivated recent graduate to join a dynamic research environment to interrogate the biophysical properties of antibody-antigen binding interactions to provide insights into the mechanisms of protective immunity.

Monday, August 31, 2015
Postdoctoral Associate, Applied Genomics & Precision Medicine Duke Center for Applied Genomics & Precision Medicine, DOM

The postdoctoral position will reside in the Duke Center for Applied Genomics & Precision Medicine within the Department of Medicine. The qualified candidate will work within applied genomic medicine programs focusing on development of novel statistical models and analytical methods from high-dimensional genomic and clinical datasets, including (RNA) sequencing data, microarray data, multiplex PCR data or other complex ‘omic’ datasets. The work may also extend to text mining and pathways analysis. This position is available for immediate hire.

Additional Scope: The candidate will be expected to develop novel statistical and machine learning methodologies tailored to utilize the multi dimensional data and to address medical / translational problems. It is anticipated that there will be a wide variety of statistical and machine learning methodologies that are relevant to these problems. The candidate will need to be able to remain current in the literature in these fields and it is expected that s/he will spend at least 50% time researching and developing novel analysis methodologies. Remaining effort will be spent in collaborative work with physicians and biologists within the applied genomic medicine programs supporting refinement and interpretation of analytical results from biological and clinical studies and activities destined for publication. The candidate is expected to develop research results into quality manuscripts for submission to peer-reviewed journals, and for presentation at relevant scientific meetings or conferences. The candidate is expected to participate in regular group or project team meetings, and present and discuss research results as necessary. The successful candidate will be an integral member of any team of investigators working on the genomics project(s) from which the data is derived.

Monday, August 31, 2015
Postdoctoral Associate, Epigenetics and Cancer Cell Biology

A postdoctoral associate position is available at the Yildirim Lab at Duke Department of Cell Biology. We are looking for creative, accomplished and highly motivated applicants who are interested in research involving noncoding RNA mediated epigenetic mechanisms of gene expression in mammalian systems, and the role of these processes in cancer. 

Friday, October 23, 2015
Postdoctoral Associate, Civil and Environmental Engineering Duke Department of Civil and Environmental Engineering

The project team of Dr. Marc Deshusses at Duke University in collaboration with Dr. Bill Jacoby at the University of Missouri has built a Supercritical Water Oxidation (SCWO) Processing reactor in a 20' shipping container on the Duke campus in Durham, NC.  The project receives funding from the Bill and Melinda Gates foundation as part of the Reinvent the Toilet Initiative aimed at improving sanitation in developing countries as well as from the USDA for investigating treatment of animal waste. The SCWO Process Engineer will be a key member of a small, focused team that will rigorously and methodically characterize the prototype reactor on different feedstock. Value engineering and process modeling will be conducted to optimize design and process parameters to minimize energy requirements while enhancing system performance and reliability.  System design and component selection will be evaluated to maximize the potential for low cost manufacturing and sustainability.  A techno-economic evaluation will assess the commercial viability of the system in different markets. 

Friday, September 4, 2015
Postdoctoral Associate, Duke Molecular Genetics and Microbiology Molecular Genetics and Microbiology/Neurobiology

Postdoctoral position is available in the laboratory of Dong Yan ( Our laboratory focuses on dissecting molecular mechanisms of neural circuit formation, regulation and degeneration in C. elegans. We apply classic genetic manipulation combined with live imaging and biochemical approaches to uncover key insights into neural circuit formation in young animals and neural degeneration in old animals. We currently have projects focusing on the following areas: i) RME circuit formation; ii) gap junction dynamics; iii) aging related neurodegeneration .

Wednesday, September 30, 2015
Postdoctoral Associate, Immunology Immunology, Duke University Medical Center

The Ciofani lab studies the transcriptional regulatory networks that govern inflammatory immune cell development and function.  We are seeking motivated, talented candidates for full-time postdoctoral positions to be held in the Department of Immunology, Duke University Medical Center.   Positions are immediately available in two exciting project areas: (1)  A National Multiple Sclerosis Society-funded position aimed at identifying novel genetic mediators of multiple sclerosis (MS).  The project applies an integrative network approach, combining regulatory information from global transcriptomic and chromatin conformation measurements of human CD4 T cells with genome wide association study data to identify and prioritize MS risk-linked genes.  The researcher will apply established protocols as well as develop novel methodologies to achieve this goal.  The study will involve high-throughput sequencing; CRISPR/Cas9 genome targeting; and screening of gene candidates in mouse models of MS, thus providing the successful fellow with experience in several cutting-edge techniques.  The ideal candidate will have a strong background in immunology and/or molecular biology; and be interested in managing an interdisciplinary project focused on the generation and computational analysis of large data sets.(2)  The gene regulatory mechanisms governing inflammatory T cell development, plasticity, and function.  Our focus is on the role of AP-1 family transcription factors and non-coding RNAs.  The researcher will take advantage of cell culture methods; global genomic regulatory assessments (RNA, accessibility, transcription factor occupancy); and in vivo models of infection and autoimmune disease in gene-deficient animals to perform functional and mechanistic studies.Appointments will be made on a renewable one-year contract with the expectation of at least a three-year commitment.   Positions are available immediately and will be filled as soon as possible.

Friday, July 31, 2015
Postdoctoral Associate, Genetic Association Studies of Human Health, Aging, and Lifespan Duke Social Sciences Research Institute

An exciting research opportunity is available at the Biodemography of Aging Research Unit, Social Sciences Research Institute, Duke University for a National Institute on Aging (NIA) funded project. Our research team is looking for an open-minded and talented post-doc who is excited about aging-related science. Candidate should be able to perform multiple tasks in a multi- and inter-disciplinary environment and to apply integrative approaches in studies of complex research questions in genetic susceptibility to human aging, age-related diseases and lifespan.The research agenda will include (but not limited to) working with large-scale datasets with phenotypic and genetic information, statistical analyses of these data, analytic work with the results, functional genomics analyses, mathematical modeling, and publishing scientific papers. Particular focus will be on the analyses of associations of SNPs with heath and aging/longevity related traits and on addressing the relationships among genetic regulators of physiological aging, senescence, health and lifespan, using several large longitudinal human datasets.

Friday, September 25, 2015
Postdoctoral Associate, Biomedical Engineering Biomedical Engineering, Pratt School, Duke University

The Randles lab has an immediate opening for a Postdoctoral Associate to conduct applied research in the area of large-scale hemodynamic simulations. We are interested in questions that are of crucial importance for vascular disease reserach, and we use mathematical and computational techniques to approach them. In particular, we are coupling a kinetic representation of fluid mechanics with a deformable representation of suspended bodies and vessel walls to create patient-specific simulations of hemodynamics. Such methods are extremely computationally intense and requre use of large-scale supercomputers.  The focus of the candidate will be on the development and application of multiscale/multiphysics software to study the localization and progression of disease. The position is available for immediate hire with a 2-year term and opportunity for additional annual renewal contingent on performance and funding availability. 

Tuesday, September 15, 2015
Research Scientist, Duke Viral Vector Core Viral Vector Core, Duke Department of Neurobiology

The Duke University School of Medicine Viral Vector Core (VVC) seeks to hire a Research Scientist to direct activities of the Core. The VVC is based in the Department of Neurobiology at the Duke University Medical Center and serves the Duke community in the design and preparation of custom viral vectors (e.g. adeno-associated virus, lentivirus, rabies virus) for laboratory research purposes. Responsibilities of the position include working with investigators to provide guidance on development of viral constructs that will meet their research needs, development and optimization of new viral vector methodologies, design and construction of custom viral vectors, preparation of viral stocks for core facility customers, supervision of VVC facility personnel, and oversight for financial management of the VVC. Further description of the VVC and its mission can be viewed at

Friday, July 31, 2015
Postdoctoral Associate, Duke Cancer Institute, Duke University Medical Center Duke Cancer Institute, Duke University Medical Center

A full time postdoctoral position is available in the Genitourinary (GU) Oncology Research Laboratory to study molecular mechanisms underlying tumor aggressiveness. The Laboratory focuses on preclinical studies, correlative science with archived clinical trial specimens and prospective specimen collections and analyses to further understand the biology underlying GU malignancies and to discover better treatment options for patients. The Laboratory is situated in an open laboratory setting with interactive and collaborating scientists at all academic levels.  Some studies will be done in collaboration with the David H. Murdock Research Institute and Core Laboratory. The research involves RT-PCR, targeted sequencing and circulating nucleic acid and small molecule profiling from blood specimens from Caucasian American and African American men who have developed prostate cancer and those who have not developed prostate cancer. Researchers have access to all essential instrumentation for the study.

Friday, August 28, 2015


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