Postdoc Positions at Duke

Below are some of the postdoctoral positions available at Duke University. Please note that this list is NOT comprehensive. If you do not see a position in your area of interest, you should directly contact Duke faculty who are working in your research area(s) to inquire about possible positions.

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual’s age, color, disability, genetic information, gender, gender identity, national origin, race, religion, sexual orientation, or veteran status.

Position Title Department Job Description Deadline to apply
Postdoctoral Associate, Cancer Genomics Duke Department of Surgery

A Postdoctoral Associate position is available at the Duke Center for Applied Therapeutics, Duke University, Durham, NC.  The Postdoctoral Associate will work closely with Drs. Qing Cheng and H. Kim Lyerly to carry out independent research. The focus of our research is translational medicine in primary breast cancer with emphasis on next-generation sequencing in the characterization of tumor heterogeneity, as well as non-invasive approaches for the detection and diagnosis of aggressive tumors for targeted therapy/immunotherapy.

Friday, June 10, 2016
Postdoctoral Associates, Cell and Gene Therapy for Cardiac Arrhythmias Duke Biomedical Engineering and Cardiology

Postdoctoral openings in gene- and cell-based therapy for cardiac arrhythmias and myocardial infarction are immediately available in Bursac lab (http://bursaclab.pratt.duke.edu/). We are looking for highly motivated candidates with expertise in cell and molecular biology, single cell electrophysiology, optical mapping of action potential propagation in Langendorff-perfused hearts, and small or large animal studies. The project involves development of novel in situ and exogenous cell- and gene-based therapies for cardiac arrhythmias and will include work in ion channel engineering, genetic manipulation of excitable and unexcitable cells, and application of tissue and genetic engineering techniques to improve electrical conduction and prevent or terminate arrhythmias in injured or chronically diseased hearts. Post-myocardial infarction induced VT and chronic AF will be the two main applications of this work.

Sunday, July 31, 2016
Postdoctoral Associate, Genome Editing for Striated Muscle Regeneration Duke Biomedical Engineering and Cardiology

Immediate postdoctoral openings in genome editing for regeneration of striated (cardiac or skeletal) muscle are available in Bursac lab (http://bursaclab.pratt.duke.edu/). We are looking for highly motivated candidates with experience in genome engineering technology, including CRISPR/Cas9 editing, and next generation sequencing. The main therapeutic application will involve endogenous or stem cell-based regeneration of infarcted heart and injured or diseased skeletal muscle. Postdoctoral fellows are expected to generate new human pluripotent stem cell lines by CRISPR/Cas9 editing, perform gRNA library screening to identify candidate effector genes, and differentiate hiPSCs into the cells of cardiovascular, skeletal muscle, or immune system lineage. Tissue engineering of human cardiac and skeletal muscle from hiPS cells will be further applied for disease modeling (cardiomyopathy, Pompe disease, DMD), in vitro mechanistic studies, and in vivo regenerative therapy applications.

Friday, July 1, 2016
Postdoctoral Associate in Medical Education, Department of Community and Family Medicine Duke University School of Medicine

Conduct independent and collaborative teaching, educational research, and administrative activities under the guidance of a faculty mentor in preparation for a full time academic career in health professions/biomedical sciences education. The ideal candidate has career aspirations to pursue a career in health professions education as their primary focus, with scholarly activities in teaching, learning and assessment, as opposed to "bench" or "translational research".  The Postdoctoral Associate will have an assigned faculty mentor who will meet with him/her regularly, and have a minimum of quarterly performance evaluations.  Working with this individual, the Postdoctoral Associate will develop an individualized learning plan, a timeline for completion, one or more academic products, and identify needed resources. The Postdoctoral Associate will report to Dr. Kathryn Andolsek, Assistant Dean for Premedical Education for the Duke School of Medicine. In addition to Dr. Andolsek, the Postdoctoral Associate will meet regularly with an assigned biomedical sciences faculty mentor and the Director of Duke AHEAD. There will be a minimum of quarterly performance evaluations by Dr. Andolsek.  The Office of Biomedical Graduate Education will provide office space. This will be a full-time position, renewable after the first year contingent on performance and funding.  The optimal expected start date is July 1, 2016.  Applicants will be considered beginning May 16, 2016 until the position is filled.Duties:

  • During the first fellowship year, the Postdoctoral Associate will assist in the design, implementation, assessment, and enhancement of biological science courses, and master the integrated human biological sciences curriculum mentored by a member of the Duke Master of Biomedical Sciences faculty.
  • During the second year, the Postdoctoral Associate will have progressive independence in designing, delivering, and assessing identified curricular components. In the final 6 months, the Postdoctoral Associate will be expected to teach an elective for which they will have designed a syllabus and identified appropriate content, pedagogy and assessment strategies.
  • The Postdoctoral Associate will be a participating associate member of Duke AHEAD (Academy for Health Professions Education and Academic Development) and is strongly encouraged to participate in relevant activities, workshops, and committees, including the Duke AHEAD certificate program.
  • The Postdoctoral Associate will develop skills in academic advisement by participating with Duke MBS faculty and MBS students.
  • The Postdoctoral Associate will complete one or more scholarly medical education project(s) to be submitted/disseminated externally (e.g. poster presentation or abstract at a national/international meeting; submission of a manuscript to a peer reviewed journal).
  • The Postdoctoral Associate will ideally be intellectually connected to their pertinent discipline with professional development and continuing education opportunities such as seminars, discipline-specific workshops, and engagement in the aligned academic community.
  • The Postdoctoral Associate will be encouraged to collaborate with other Postdoctoral Associates in Graduate Biomedical Education formally and informally.  When appropriate, they may participate in the signature programs through the Office of Biomedical Graduate Diversity: https://medschool.duke.edu/about-us/diversity-and-inclusion/office-biome....
  • The Postdoctoral Associate will apply, if relevant and consistent with learning plan, to one or more of the following professional development programs, recognizing that there is no guarantee of acceptance.
  • Emerging Leaders Institute:  https://gradschool.duke.edu/professional-development/programs/emerging-l...
  • Bass Instructional Fellowship https://gradschool.duke.edu/professional-development/programs/bass-instr....
Friday, June 24, 2016
Postdoctoral Associates, Molecular Pathology/Molecular Biology Duke Department of Surgery

Two Postdoctoral Research Fellow training positions are available in the laboratory of Dr. H. Kim Lyerly at the Duke Center for Applied Therapeutics.  These positions will be in conjunction/collaboration with pathologist Dr. Edgardo R. Parrilla Castellar at the Duke Molecular Diagnostics Laboratory, and molecular biologist Dr. Greg Hannon, Cambridge University, and will focus on breast cancer immune-oncology.  Current research efforts focus on innovative, non-invasive approaches for the detection and diagnosis of breast cancer, with ultimate goal of distinguishing biologically aggressive tumors for targeted therapy/immunotherapy.  This fellowship will specifically 1) explore the genomic changes leading to neo-antigens in breast cancer and 2) characterize tumor-associated immune-infiltrates using a molecular genetic approach. Resources include platforms for massively parallel DNA sequencing and genomic/expression arrays, plus an annotated source of tissues is available for the study.  Reporting to the Duke Center for Applied Therapeutics efforts to characterize novel biomarkers and manuscript submission(s) are expected.  Duties and responsibilities may include: 

  • Perform standard technical procedures such as PCR, qPCR, and electrophoresis.
  • Perform DNA extraction from fresh-frozen and/or paraffin-embedded tissue, plasma or other non-cellular compartments.
  • Operate capillary analyzer, next-generation sequencing platform, and/or DNA microarray machine.
  • Design and establish a library preparation solution for targeted DNA or RNA massively-parallel sequencing.
  • Organize and perform integrative analysis of complex genetic and morphologic data, including computational and/or statistical analysis.
  • Establish and execute a validation/verification plan using validation samples using results of the biomarker discovery phase.
Tuesday, May 31, 2016
Postdoctoral Associate - Tumor Immunology/Immunotherapy Department of Medicine, Duke University Medical Center

The Hanks Lab is a basic/translational research lab in the Duke Cancer Institute with an interest in understanding cancer immune evasion and immunotherapy resistance.   We are seeking a motivated, hardworking postdoctoral candidate with a background in immunology to lead projects investigating cancer vaccine development and checkpoint inhibitor immunotherapy resistance. The candidate will be expected to work independently but also collaborate with other lab members in a team environment.

Friday, June 3, 2016
Postdoctoral Associate (Substance Use/Addiction, Clinical Trials, Epidemiology) Department of Psychiatry and Behavioral Sciences

Funded by the NIDA, the Mid Southern Primary Care Networks Node of National Drug Abuse Treatment Clinical Trials Network (NIDA CTN) is seeking a highly motivated postdoctoral research associate to join the study team. Responsibilities include assisting with project activities, conducting statistical analysis of research datasets, conducting literature reviews, preparing reports, writing/publishing manuscripts, and assisting with other project work as assigned. 

Wednesday, August 31, 2016
Postdoctoral Associate, Vascular Biology Duke Internal Medicine-Cardiology

 The primary goal of Dr. Francis Miller’s research program is to understand the role of the NADPH oxidases in vascular disease. Ongoing studies include (1) identifying molecular mechanisms of NADPH oxidase regulation; (2) determining whether chronic inflammation accelerates vascular disease via activation of an EGFR-NADPH oxidase pathway; (3) understanding how microRNA-mediated changes in NADPH oxidase coordinate pathways implicated in vascular disease; and (4) identifying RNA aptamers for vascular cell-specific delivery of therapeutics. 

Thursday, June 30, 2016
Postdoctoral Associate, Medicine / Medical Oncology Medicine / Medical Oncology, Duke Cancer Institute

The Hanks Lab is a growing basic/translational research lab in the Duke Cancer Institute, Duke University Medical Center, with an interest in understanding cancer immune evasion and immunotherapy resistance.   We are seeking a motivated, hardworking Postdoctoral Associate with a background in tumor immunology and bioinformatics to lead the pre-clinical development of a novel dendritic cell-based cancer vaccine while also spearheading our efforts to utilize RNAseq differential gene expression and other methodologies to better understand the evolution of checkpoint inhibitor resistance in advanced melanoma patients. The candidate will be expected to work independently but also collaborate with other lab members in a team working environment.   

Thursday, June 30, 2016
Postdoctoral Associate, Medicine - Rheumatology and Immunology Duke Department of Medicine

The Donghai Wang group (https://medicine.duke.edu/faculty/donghai-wang-phd) in the Department of Medicine-Rheumatology and Immunology, Duke University School of Medicine, seeks a Postdoctoral Associate. We are seeking an enthusiastic individual to join the recently established laboratory dedicated to the study of human autoinflammatory diseases. We use the state of the are modern research tools to elucidate the dysregulation of innate immune responses that culminate in human inflammatory diseases. We are currently focused on how the cholesterol biosynthesis pathway may affect inflammation.

Tuesday, May 31, 2016

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